Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogène
This P450R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-488 amino acids from the Central region of human P450R.
CYP2B6
Reactivité: Humain, Souris
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Restrictions
For Research Use only
Format
Liquid
Concentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
CYP2B6
(Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))
anticorps CPB6, anticorps CYP2B, anticorps CYP2B7, anticorps CYP2B7P, anticorps CYPIIB6, anticorps EFVM, anticorps IIB1, anticorps P450, anticorps CPF3, anticorps CYP4F, anticorps LTB4H, anticorps CYP2B30, anticorps CYP2B11, anticorps CYPIIB11, anticorps 21-OH, anticorps 21OH, anticorps 21OHA, anticorps 21OHB, anticorps CYP21OH-A, anticorps Cyp21, anticorps Cyp21-ps1, anticorps Cyp21B, anticorps Cyp21a2-ps, anticorps Cyp21a2ps, anticorps Oh21-1, anticorps Oh21-2, anticorps CYP2B6, anticorps cytochrome P450 family 2 subfamily B member 6, anticorps cytochrome P450 family 4 subfamily F member 3, anticorps cytochrome P450, family 2, subfamily B, polypeptide 6, anticorps cytochrome P450 family 2 subfamily B member 6 L homeolog, anticorps cytochrome P450 2B11, anticorps cytochrome P450, family 21, subfamily a, polypeptide 1, anticorps cytochrome P450 subfamily 2B, anticorps cytochrome P450 2B11-like, anticorps CYP2B6, anticorps CYP4F3, anticorps cyp2b6.L, anticorps Cyp21a1, anticorps LOC100068603
Sujet
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.