T-Box 1 anticorps (C-Term)

N° du produit ABIN5534725

Détail du produit anti-T-Box 1 anticorps

Antigène: T-Box 1 (TBX1)

Épitope: AA 327-356, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Box 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-356 amino acids from the C-terminal region of human TBX1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IHC-P starting dilution is: 1:25

For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur T-Box 1

Antigène: T-Box 1 (TBX1)

Autre désignation: TBX1 (TBX1 Produits)

Synonymes: anticorps CAFS, anticorps CTHM, anticorps DGCR, anticorps DGS, anticorps DORV, anticorps TBX1C, anticorps TGA, anticorps VCFS, anticorps mp:zf637-3-000616, anticorps zgc:136724, anticorps TBX1, anticorps dgs, anticorps tga, anticorps cafs, anticorps cthm, anticorps dgcr, anticorps dorv, anticorps vcfs, anticorps tbx1c, anticorps xtbx1, anticorps tbx1, anticorps T-box 1, anticorps T-box 1 S homeolog, anticorps T-box 1 L homeolog, anticorps TBX1, anticorps Tbx1, anticorps tbx1, anticorps tbx1.S, anticorps tbx1.L

Sujet: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 43 kDa

ID gène: 6899

UniProt: O43435

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation