WNT6 anticorps (AA 173-201)

N° du produit ABIN5534827

Détail du produit anti-WNT6 anticorps

Antigène: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Épitope: AA 173-201

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT6 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This WNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human WNT6.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur WNT6

Antigène: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Autre désignation: WNT6 (WNT6 Produits)

Synonymes: anticorps WNT6, anticorps si:dkey-31m21.2, anticorps Wnt6, anticorps AA409270, anticorps Wnt-6, anticorps Xwnt-6, anticorps wnt-6, anticorps wnt6-A, anticorps xWnt6, anticorps Wnt family member 6, anticorps wingless-type MMTV integration site family, member 6b, anticorps wingless-type MMTV integration site family, member 6, anticorps Wnt family member 6 S homeolog, anticorps WNT6, anticorps Wnt6, anticorps wnt6b, anticorps wnt6.S

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.

Poids moléculaire: 40 kDa

ID gène: 7475

UniProt: Q9Y6F9

Pathways: Signalisation WNT, Tube Formation