CYP24A1 anticorps (C-Term)

N° du produit ABIN5535096

Détail du produit anti-CYP24A1 anticorps

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Épitope: AA 466-494, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP24A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This CYP24A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human CYP24A1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CYP24A1

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Autre désignation: CYP24A1 (CYP24A1 Produits)

Synonymes: anticorps CP24, anticorps CYP24, anticorps HCAI, anticorps P450-CC24, anticorps 24-OHase, anticorps Cyp24, anticorps 25-hydroxyvitaminD324-hydroxylase, anticorps VITD12, anticorps CP450CC24, anticorps cytochrome P450 family 24 subfamily A member 1, anticorps cytochrome P450, family 24, subfamily a, polypeptide 1, anticorps cytochrome P450, family 24, subfamily A, polypeptide 1, anticorps CYP24A1, anticorps Cyp24a1

Sujet: CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.

Poids moléculaire: 59 kDa

ID gène: 1591

UniProt: Q07973

Pathways: Metabolism of Steroid Hormones and Vitamin D