This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This EDEM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-802 amino acids from the C-terminal region of human EDEM3.
EDEM3
Reactivité: Rat
IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 555
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.43 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
anticorps RGD1561496, anticorps C1orf22, anticorps 2310050N11Rik, anticorps ER degradation enhancing alpha-mannosidase like protein 3, anticorps ER degradation enhancer, mannosidase alpha-like 3 L homeolog, anticorps ER degradation enhancer, mannosidase alpha-like 3, anticorps Edem3, anticorps EDEM3, anticorps edem3.L, anticorps edem3
Sujet
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).