FZD6 anticorps (AA 493-520)
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- Antigène Voir toutes FZD6 Anticorps
- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Épitope
- AA 493-520
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FZD6 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This FZD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product FZD6 Anticorps primaire
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- Indications d'application
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Autre désignation
- FZD6 (FZD6 Produits)
- Synonymes
- anticorps zgc:65879, anticorps zgc:77440, anticorps fz6, anticorps frz6, anticorps Xfrz6, anticorps frizzled6, anticorps frizzled-6, anticorps FZ-6, anticorps FZ6, anticorps HFZ6, anticorps NDNC10, anticorps Frizzled-6, anticorps Fz6, anticorps frizzled class receptor 6, anticorps frizzled class receptor 6 S homeolog, anticorps fzd6, anticorps fzd6.S, anticorps FZD6, anticorps Fzd6
- Sujet
- This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 79 kDa
- ID gène
- 8323
- UniProt
- O60353
- Pathways
- Signalisation WNT, Tube Formation
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