SUN2 anticorps (AA 237-265)

N° du produit ABIN5536431

Détail du produit anti-SUN2 anticorps

Antigène: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Épitope: AA 237-265

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUN2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UNC84B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-265 amino acids from the Central region of human UNC84B.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SUN2

Antigène: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Autre désignation: UNC84B (SUN2 Produits)

Synonymes: anticorps UNC84B, anticorps B230369L08Rik, anticorps C030011B15, anticorps Unc84b, anticorps RGD1563141, anticorps Sad1 and UNC84 domain containing 2, anticorps SUN2, anticorps Sun2

Sujet: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1, MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM].

Poids moléculaire: 80 kDa

ID gène: 25777

UniProt: Q9UH99

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2