USP8 anticorps (C-Term)
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- Antigène Voir toutes USP8 Anticorps
- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
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Épitope
- AA 1058-1087, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp USP8 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Immunogène
- This USP8 (UBPY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1058-1087 amino acids from the C-terminal region of human USP8 (UBPY).
- Isotype
- Ig Fraction
- Top Product
- Discover our top product USP8 Anticorps primaire
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- Indications d'application
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
- Autre désignation
- USP8 (USP8 Produits)
- Synonymes
- anticorps HumORF8, anticorps UBPY, anticorps AI574262, anticorps AW557536, anticorps Ubpy, anticorps mKIAA0055, anticorps ubiquitin carboxyl-terminal hydrolase 8, anticorps ubiquitin specific peptidase 8, anticorps LOC9310109, anticorps MGYG_00369, anticorps USP8, anticorps Usp8
- Sujet
- Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
- Poids moléculaire
- 128 kDa
- ID gène
- 9101
- UniProt
- P40818
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