PITRM1 anticorps (AA 490-518)

N° du produit ABIN5538138

Détail du produit anti-PITRM1 anticorps

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Épitope: AA 490-518

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITRM1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.26 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PITRM1

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Autre désignation: PITRM1 (PITRM1 Produits)

Synonymes: anticorps MP1, anticorps PreP, anticorps 2310012C15Rik, anticorps AA410010, anticorps MP-1, anticorps Ntup1, anticorps mKIAA1104, anticorps PITRM1, anticorps wu:fa03d09, anticorps zgc:55469, anticorps pitrilysin metallopeptidase 1, anticorps pitrilysin metallepetidase 1, anticorps pitrilysin metallopeptidase 1 L homeolog, anticorps PITRM1, anticorps Pitrm1, anticorps pitrm1.L, anticorps pitrm1

Sujet: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Poids moléculaire: 117 kDa

ID gène: 10531

UniProt: Q5JRX3

Pathways: Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome