CD2AP anticorps

N° du produit ABIN5647746

Détail du produit anti-CD2AP anticorps

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD2AP est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids K253-K337 was used as the immunogen for the CD2AP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CD2AP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CD2AP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CD2AP

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Autre désignation: CD2AP (Cd2ap Produits)

Synonymes: anticorps cd2apl, anticorps fj51c01, anticorps im:7153970, anticorps si:ch211-207n9.1, anticorps wu:fj51c01, anticorps zgc:103705, anticorps DKFZp469E061, anticorps CMS, anticorps AL024079, anticorps C78928, anticorps METS-1, anticorps Mets1, anticorps CD2-associated protein L homeolog, anticorps CD2 associated protein, anticorps CD2-associated protein, anticorps cd2ap.L, anticorps CD2AP, anticorps cd2ap, anticorps Cd2ap

Sujet: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

UniProt: Q9Y5K6