MGEA5 anticorps (AA 236-269)

N° du produit ABIN5647928

Détail du produit anti-MGEA5 anticorps

Antigène: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Épitope: AA 236-269

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGEA5 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée (Details): Expected species reactivity: Mouse,Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 236-269 from human MGEA5 was used as the immunogen for the MGEA5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the MGEA5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MGEA5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MGEA5

Antigène: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Autre désignation: MGEA5 (MGEA5 Produits)

Synonymes: anticorps MEA5, anticorps NCOAT, anticorps OGA, anticorps 2810009A20Rik, anticorps 4833427O07Rik, anticorps 5830447M11Rik, anticorps AA408215, anticorps Hy5, anticorps Ncoat, anticorps mKIAA0679, anticorps O-GLCNACASE, anticorps cytochrome c oxidase subunit VIc, anticorps meningioma expressed antigen 5 (hyaluronidase), anticorps COX6C, anticorps MGEA5, anticorps Mgea5

Sujet: Isoform 1 (Cytoplasmic): Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:< a href=http://www.uniprot.org/citations/11148210 target=_blank>11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:< a href=http://www.uniprot.org/citations/24088714 target=_blank>24088714).

Isoform 3 (Nuclear): Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1. [UniProt]

UniProt: O60502

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process