ACVR2A anticorps (C-Term)

N° du produit ABIN5671355

Détail du produit anti-ACVR2A anticorps

Antigène: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR2A est non-conjugé

Application: Western Blotting (WB)

Séquence: AYLHEDIPGL KDGHKPAISH RDIKSKNVLL KNNLTACIAD FGLALKFEAG

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against AVR2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AVR2A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ACVR2A

Antigène: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Autre désignation: AVR2A (ACVR2A Produits)

Synonymes: anticorps ACVR2, anticorps ACVR2A, anticorps XSTK9, anticorps actrii, anticorps acvr2, anticorps ACTRII, anticorps Acvr2, anticorps rActR-II, anticorps actr2a, anticorps acvr2a, anticorps wu:fa02e10, anticorps ActrIIa, anticorps TactrII, anticorps activin A receptor type 2A, anticorps activin A receptor type 2A L homeolog, anticorps activin A receptor type 2Aa, anticorps activin receptor IIA, anticorps ACVR2A, anticorps acvr2a, anticorps Acvr2a, anticorps acvr2a.L, anticorps acvr2aa

Sujet: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Alias Symbols: ACVR2A, ACVR2,

Protein Interaction Partner: BMP10, GDF2, ACVR1, INHBA, PEG10, ERBB2IP, UBC, IGSF1, MAGI2, TCTEX1D4, SYNJ2BP, GDF9, ACVRL1, INHBC, GDF5, TGFBR3, INHBB, ENG, BMP7, BMP6, ACVR1B, INHA,

Protein Size: 513

ID gène: 92

NCBI Accession: NP_001607

UniProt: P27037