AGE anticorps

N° du produit ABIN5680158

Détail du produit anti-AGE anticorps

Antigène: AGE (Advanced Glycation End Products (AGE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGE est non-conjugé

Application: ELISA

Specificité: Advanced Glycation End Products (AGE), cross-reactivity BSA-AGE, HSA-AGE <1 %

Réactivité croisée (Details): Human, rat. Broad reactivity with advanced glycation end products (AGE) in many species.

Attributs du produit: This antibody is suitable for the detection of different AGE products in tissues, tissue extracts and body fluids. Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in (i) human lens, (ii) renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, (iii) atherosclerotic lesions of arterial walls, (iv) ß2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and (v) brain tissues of patients with Alzheimer's disease. These results suggested the potential role of AGE in normal aging and age-enhanced disease processes. Advanced Glycation End Products (AGE), cross-reactivity BSA and HSA <1 % .

Purification: Protein A affinity purified IgG

Immunogène: Advanced Glycation End Products /BSA/HSA

Isotype: IgG

Information d'application

Indications d'application: human lens, arteriosclerotic plaques,ELISA, IHC not established,60 min at RT or 18 hr at 2-8 °C,(liquid conc.) ELISA app. 1 μg/mL, (IHC 5-10 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS 0.05 M,  pH 7.15, 0.85 % NaCl, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur AGE

Antigène: AGE (Advanced Glycation End Products (AGE))

Autre désignation: AGE, Advanced Glycation End Products (AGE Produits)

Synonymes: anticorps RBP, anticorps RNBP, anticorps renin binding protein, anticorps RENBP

Classe de substances: Chemical