DcR1 anticorps

N° du produit ABIN5688393

Détail du produit anti-DcR1 anticorps

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DcR1 est non-conjugé

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificité: Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.

Pureté: > 95% (SDS-PAGE)

Immunogène: Recombinant human TRAIL-R3 (DcR1).

Clone: HS301

Isotype: IgG1

Information d'application

Indications d'application: Definition for 1 test: 1 μL of labeled antibody in 200 μL of Flow Cytometry buffer (see online protocol).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for at least 1 year after receipt when stored at -20°C.

Détails sur DcR1

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Autre désignation: TRAIL-R3 (TNFRSF10C Produits)

Synonymes: anticorps CD263, anticorps DCR1, anticorps DCR1-TNFR, anticorps LIT, anticorps TRAIL-R3, anticorps TRAILR3, anticorps TRID, anticorps TNFRSF10C, anticorps TNF receptor superfamily member 10c, anticorps TNFRSF10C

Sujet: TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

ID gène: 8794

UniProt: O14798

Pathways: Apoptose