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PRKAA1 anticorps (AA 485-489)
PRKAA1
Reactivité: Humain, Souris, Rat
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5689419
Détail du produit anti-PRKAA1 anticorps
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Antigène
Voir toutes PRKAA1 Anticorps
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Épitope
Tous les épitopes à travers PRKAA1 Anticorps.
AA 485-489
Reactivité
Toutes les réactivités sur PRKAA1 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur PRKAA1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur PRKAA1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PRKAA1 Anticorps
Cet anticorp PRKAA1 est non-conjugé
Application
Tous les applications à travers PRKAA1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Specificité
This antibody detects endogenous level of total AMPKα,1 protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogène
AMPKa1 (Ab-487) antibody was raised in was raised against a peptide sequence around aa.485~489 (S-G-S-V-S) derived from Human AMPKα,1.
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Information d'application
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Indications d'application
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store antibody at -20°C for up to one year.
Détails sur PRKAA1
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Antigène
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Autre désignation
AMPKa1 (PRKAA1 Produits )
Synonymes
anticorps AMPK, anticorps AMPKa1, anticorps cb116, anticorps im:7154392, anticorps sb:cb130, anticorps wu:fa94c10, anticorps AMPK1, anticorps AMPKalpha1, anticorps AI194361, anticorps AI450832, anticorps AL024255, anticorps C130083N04Rik, anticorps ampk, anticorps ampka1, anticorps PRKAA1, anticorps protein kinase AMP-activated catalytic subunit alpha 1, anticorps protein kinase, AMP-activated, alpha 1 catalytic subunit, anticorps protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog, anticorps PRKAA1, anticorps prkaa1, anticorps Prkaa1, anticorps prkaa1.L
Sujet
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Poids moléculaire
63 kDa
ID gène
5562
NCBI Accession
NP_006242
UniProt
Q13131 , P54646
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , L'effet Warburg
Vus récemment
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