Caspase 3 anticorps (AA 29-33)
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- Antigène Voir toutes Caspase 3 (CASP3) Anticorps
- Caspase 3 (CASP3)
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Épitope
- AA 29-33
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Caspase 3 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects endogenous level of total Caspase 3 protein.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- Caspase 3 antibody was raised against a peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
- Top Product
- Discover our top product CASP3 Anticorps primaire
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- Indications d'application
- Western Blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Antigène
- Caspase 3 (CASP3)
- Autre désignation
- Caspase 3 (CASP3 Produits)
- Synonymes
- anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a
- Sujet
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
- Poids moléculaire
- 35 19 17 kDa
- ID gène
- 836
- NCBI Accession
- NP_004337
- UniProt
- P42574
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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