GLIS2 anticorps (AA 260-310)

N° du produit ABIN5689976

Détail du produit anti-GLIS2 anticorps

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Épitope: AA 260-310

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLIS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: GLIS2 antibody is human, mouse and rat reactive.

Purification: GLIS2 antibody is affinity chromatography purified via peptide column.

Immunogène: GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2.

The immunogen is located within amino acids 260 - 310 of GLIS2.

Isotype: IgG

Information d'application

Indications d'application: GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GLIS2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GLIS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GLIS2

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Autre désignation: GLIS2 (GLIS2 Produits)

Synonymes: anticorps glis2b, anticorps nkl-A, anticorps xNKLb, anticorps NKL, anticorps NPHP7, anticorps Gli5, anticorps Klf16, anticorps Nkl, anticorps glis2a, anticorps nphp7, anticorps GLIS family zinc finger 2 L homeolog, anticorps GLIS family zinc finger 2, anticorps GLIS family zinc finger 2 S homeolog, anticorps glis2.L, anticorps GLIS2, anticorps Glis2, anticorps glis2.S

Sujet: GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).

Poids moléculaire: Predicted: 58 kDa

Observed: 60 kDa

ID gène: 84662

NCBI Accession: NP_115964

UniProt: Q9BZE0