PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.
Purification
PACS1 antibody is affinity chromatography purified via peptide column.
Immunogène
PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1.
The immunogen is located within amino acids 430 - 480 of PACS1.
PACS1
Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye, Lapin, Roussette (Chauve-souris), Porc
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antigène
PACS1
(phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).