DYNLT1 anticorps (AA 1-80)
Aperçu rapide pour DYNLT1 anticorps (AA 1-80) (ABIN5693148)
Antigène
Voir toutes DYNLT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-80
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Fonction
- Anti-DYNLT1 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-DYNLT1 Antibody (ABIN5693148). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived human DYNLT1 recombinant protein (Position: M1-A80).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunofluorescence, 5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
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Autre désignation
- DYNLT1
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Sujet
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Synonyms: Dynein light chain Tctex-type 1, Protein CW-1, T-complex testis-specific protein 1 homolog, DYNLT1, TCTEL1, TCTEX-1, TCTEX1
Tissue Specificity: Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level).
Background: Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Poids moléculaire
- 16 kDa
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ID gène
- 6993
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UniProt
- P63172
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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