DYNLT1 anticorps

N° du produit ABIN7113673

Détail du produit anti-DYNLT1 anticorps

Antigène: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYNLT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: dynein, light chain, Tctex-type 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DYNLT1

Antigène: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Autre désignation: DYNLT1 (DYNLT1 Produits)

Synonymes: anticorps cw-1, anticorps tctel1, anticorps dynlt1a, anticorps tctex-1, anticorps MGC85297, anticorps tctex1, anticorps Ci-LC3, anticorps CW-1, anticorps TCTEL1, anticorps AGS2, anticorps Tctex1, anticorps dynein light chain Tctex-type 1 L homeolog, anticorps dynein light chain Tctex-type 1, anticorps dynein, light chain, Tctex-type 1, anticorps dynlt1.L, anticorps DYNLT1, anticorps dynlt1, anticorps Dynlt1

Sujet: Synonyms:TCTEL1, TCTEX-1, TCTEX1 Background:Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morphogenesis, the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling, the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis, inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation(By similarity).

Poids moléculaire: 12 kDa

ID gène: 6993

UniProt: P63172

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling