CLASP2 anticorps

N° du produit ABIN5697482

Détail du produit anti-CLASP2 anticorps

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: cytoplasmic linker associated protein 2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CLASP2

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Autre désignation: CLASP2 (CLASP2 Produits)

Synonymes: anticorps zgc:77279, anticorps DKFZp459M112, anticorps 1500004F14Rik, anticorps 8030404L10Rik, anticorps C77448, anticorps CLASP2beta, anticorps mKIAA0627, anticorps cytoplasmic linker associated protein 2, anticorps CLIP associating protein 2, anticorps clasp2, anticorps CLASP2, anticorps Clasp2

Sujet: Synonyms:KIAA0627 Background:Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules(PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network(TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2(PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle(PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Poids moléculaire: 140-160 kDa

ID gène: 23122

UniProt: O75122

Pathways: Dynamique des Microtubules, Maintenance of Protein Location