DKK1 anticorps

N° du produit ABIN5698859

Détail du produit anti-DKK1 anticorps

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogène: dickkopf homolog 1 (Xenopus laevis)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

human placenta tissue were subjected to SDS PAGE followed by western blot with FNab02401(DKK1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur DKK1

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Autre désignation: DKK1 (DKK1 Produits)

Synonymes: anticorps DKK-1, anticorps SK, anticorps AI414495, anticorps SGY, anticorps SGY-1, anticorps SGY1, anticorps Soggy, anticorps mSgy, anticorps dkk1, anticorps dkk, anticorps dkk-1, anticorps xdkk1, anticorps Xdkk-1, anticorps Dickkopf1, anticorps dickkopf-1, anticorps mdkk-1, anticorps dkk1-A, anticorps dickkopf WNT signaling pathway inhibitor 1, anticorps dickkopf like acrosomal protein 1, anticorps dickkopf-related protein 1, anticorps dickkopf-like 1, anticorps dickkopf WNT signaling pathway inhibitor 1b, anticorps dickkopf protein, anticorps dickkopf WNT signaling pathway inhibitor 1 S homeolog, anticorps DKK1, anticorps Dkk1, anticorps DKKL1, anticorps LOC100228789, anticorps Dkkl1, anticorps dkk1b, anticorps dkk1, anticorps dickkopf, anticorps dkk1.S

Sujet: Synonyms:Dickkopf 1, Dickkopf related protein 1, DKK 1, DKK1, hDkk 1, SK Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Poids moléculaire: 30-35 kDa

ID gène: 22943

UniProt: O94907

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation