UBA52 anticorps

N° du produit ABIN5699090

Détail du produit anti-UBA52 anticorps

Antigène: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA52 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Immunogène: ubiquitin A-52 residue ribosomal protein fusion product 1

Isotype: IgG

Information d'application

Indications d'application: IHC : 1:20-1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur UBA52

Antigène: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Autre désignation: UBA52 (UBA52 Produits)

Synonymes: anticorps CEP52, anticorps HUBCEP52, anticorps L40, anticorps RPL40, anticorps D8Ertd21e, anticorps Gm1863, anticorps Rps27a, anticorps Ubb, anticorps Ubc, anticorps UBCEP2, anticorps UB-RPL40, anticorps MGC80109, anticorps cep52, anticorps hubcep52, anticorps rpl40, anticorps RPS27A, anticorps UBB, anticorps UBC, anticorps wu:fa91f08, anticorps zgc:123344, anticorps UBA52, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog, anticorps UBA52, anticorps Uba52, anticorps uba52.L, anticorps uba52

Sujet: Synonyms:UBA52, UBCEP2, HUBCEP52, CEP52, RPL40 Background:Ubiquitin: Exists either covalently attached to another protein, or free(unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer(monoubiquitin), a polymer linked via different Lys residues of the ubiquitin(polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin(linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD(endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free(unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling. 60S ribosomal protein L40: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.

Poids moléculaire: 45kDa

ID gène: 7311

UniProt: P62987

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation