MAP3K3 anticorps

N° du produit ABIN5701066

Détail du produit anti-MAP3K3 anticorps

Antigène: MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: mitogen-activated protein kinase kinase kinase 3

Isotype: IgG

Information d'application

Indications d'application: WB : 1:200-1:1000 IHC : 1:50-1:500

Commentaires:

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab09784( MAP3K3 Antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Détails sur MAP3K3

Antigène: MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))

Autre désignation: MAP3K3 (MAP3K3 Produits)

Synonymes: anticorps MAPKKK3, anticorps MEKK3, anticorps AW548911, anticorps Mekk3, anticorps mKIAA4031, anticorps mitogen activated protein kinase kinase kinase 3, anticorps mitogen-activated protein kinase kinase kinase 3, anticorps Map3k3, anticorps MAP3K3, anticorps map3k3

Sujet: Synonyms:MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, MEKK3 Background:The mitogen-activated protein/ERK kinase kinase 3(MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen-activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases.(PMID: 18206350).Cerebral cavernous malformations(CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics.

Poids moléculaire: 36kDa

UniProt: Q99759

Pathways: Signalisation MAPK