RUNX1T1 anticorps
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- Antigène Voir toutes RUNX1T1 Anticorps
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RUNX1T1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity purified
- Immunogène
- A recombinant human protein corresponding to amino acids T335-D510 was used as the immunogen for the RUNX1T1 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product RUNX1T1 Anticorps primaire
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- Indications d'application
- Optimal dilution of the RUNX1T1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the RUNX1T1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- Autre désignation
- RUNX1T1 (RUNX1T1 Produits)
- Synonymes
- anticorps MTG8, anticorps si:ch211-232j17.1, anticorps wu:fi14b07, anticorps zgc:154044, anticorps AML1T1, anticorps CBFA2T1, anticorps CDR, anticorps ETO, anticorps ZMYND2, anticorps Cbfa2t1h, anticorps Cbfa2t1, anticorps runt-related transcription factor 1; translocated to, 1 (cyclin D-related), anticorps RUNX1 translocation partner 1 L homeolog, anticorps RUNX1 translocation partner 1, anticorps runx1t1, anticorps runx1t1.L, anticorps RUNX1T1, anticorps Runx1t1
- Sujet
- Protein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene. This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
- UniProt
- Q06455
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