PCSK6 anticorps (AA 637-648)
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- Antigène Voir toutes PCSK6 Anticorps
- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
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Épitope
- AA 637-648
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Reactivité
- Humain, Lapin
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCSK6 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Marque
- IHC-plus™
- Specificité
- Human PCSK6 / PACE4. This antibody is expected to recognize reported isoforms a, b, g and h (NP_002561.1, NP_612192.1, NP_612193.1, NP_612194.1 resp.).
- Homologie
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Rabbit (100%) Marmoset (92%) Mouse, Rat, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum (83%).
- Purification
- Immunoaffinity purified
- Immunogène
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Synthetic peptide C-YHTFSAHQSRSR from an internal region of human PCSK6 / PACE4 (NP_002561.1, NP_612192.1, NP_612195.1, NP_612197.1, NP_612196.1, NP_612198.2, NP_612193.1, NP_612194.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Rabbit (100%), Marmoset (92%), Mouse, Rat, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum (83%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product PCSK6 Anticorps primaire
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- Indications d'application
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Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:32000)
Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Preliminary experiments gave an approx 40-45 kD band in Human Brain (Cerebellum) lysates after 0.2 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 106 kD according to NP_002561.1. The 40-45 kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported? - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Minimize freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze-thaw cycles.
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- Antigène
- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
- Autre désignation
- PACE4 / PCSK6 (PCSK6 Produits)
- Synonymes
- anticorps PACE4, anticorps PCSK6, anticorps SPC4, anticorps C86343, anticorps Pace4, anticorps Spc4, anticorps PACE4AIIa, anticorps Xpace4, anticorps spc4, anticorps proprotein convertase subtilisin/kexin type 6, anticorps peptidase S8, anticorps proprotein convertase subtilisin/kexin type 6 L homeolog, anticorps PCSK6, anticorps EAMY_RS27925, anticorps pcsk6, anticorps Pcsk6, anticorps pcsk6.L
- Sujet
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Name/Gene ID: PCSK6
Subfamily: Serine S8
Family: Protease
Synonyms: PCSK6, PACE4, SPC4 - ID gène
- 5046
- NCBI Accession
- NP_002561, NP_612192, NP_612195, NP_612197, NP_612196, NP_612198, NP_612193, NP_612194
- UniProt
- P29122
- Pathways
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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