DcR1 anticorps (PE)

N° du produit ABIN576916

Détail du produit anti-DcR1 anticorps (PE)

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DcR1 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificité: Recognizes human CD263, a 60 Kd cell surface protein, which is otherwise known as decoy receptor 1 (DcR1). CD263 is a member of the tumor necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumor cells. Does not inhibit DcR1 (CD263) inhibitory function in TRAIL-induced apoptosis.

Purification: Affinity purified

Immunogène: DcR1-Fc Chimeric protein.

Clone: 2B8

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo (1:1 - 1:10), IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 4°C, avoid freezing.

Détails sur DcR1

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Autre désignation: TNFRSF10C / TRAIL-R3 / DCR1 (TNFRSF10C Produits)

Synonymes: anticorps CD263, anticorps DCR1, anticorps DCR1-TNFR, anticorps LIT, anticorps TRAIL-R3, anticorps TRAILR3, anticorps TRID, anticorps TNFRSF10C, anticorps TNF receptor superfamily member 10c, anticorps TNFRSF10C

Sujet: Name/Gene ID: TNFRSF10C
Family: TNF Receptor

Synonyms: TNFRSF10C, CD263 antigen, CD263, Cytotoxic TRAIL receptor-3, Decoy receptor 1, DCR1, DCR1-TNFR, LIT, Lymphocyte inhibitor of TRAIL, TRAIL-R3, TRAILR3, TRAIL receptor 3, TRID

ID gène: 8794

Pathways: Apoptose