NF-kB p65 anticorps (pSer529)

N° du produit ABIN5961222

L’anticorps anti-NF-kB p65 Polyclonal Lapin est utilisé pour la détection de NF-kB p65 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour NF-kB p65 anticorps (pSer529) (ABIN5961222)

Antigène: NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NF-kB p65 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NF-kB p65 anticorps

Épitope: pSer529

Specificité: Avian reticuloendotheliosis viral (v rel) oncogene homolog A,MGC131774,NF kappa B p65delta3,NFKB3,Nuclear Factor NF Kappa B p65 Subunit,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B cells 3,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,OTTHUMP00000233473,OTTHUMP00000233474,OTTHUMP00000233475,OTTHUMP00000233476,OTTHUMP00000233900,p65,p65 NF kappaB,p65 NFkB,relA,TF65,Transcription factor p65,v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)),V rel avian reticuloendotheliosis viral oncogene homolog A,v rel reticuloendotheliosis viral oncogene homolog A (avian),V rel reticuloendotheliosis viral oncogene homolog A,nuclear factor of kappa light polypeptide gene enhancer in B cells 3,p65

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human NFkappaB-p65 around the phosphorylation site of Ser529

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NF-kB p65

Antigène: NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

Autre désignation: NFkappaB-p65

Sujet: Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel,are members of a family of transcription factors that include the two subunits of the transcription factor NFκB (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.

Poids moléculaire: 60kDa

ID gène: 5970

UniProt: Q04206

Pathways: Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins