BAX anticorps (AA 1-100)
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- Antigène Voir toutes BAX Anticorps
- BAX (BCL2-Associated X Protein (BAX))
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Épitope
- AA 1-100
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAX est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Séquence
- MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bax (NP_620116.1).
- Isotype
- IgG
- Top Product
- Discover our top product BAX Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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(Arg)9-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling." dans: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 138, (2018) (PubMed).
: "Ameliorative effects of nano-elemental selenium against hexavalent chromium-induced apoptosis in broiler liver." dans: Environmental science and pollution research international, Vol. 25, Issue 16, pp. 15609-15615, (2018) (PubMed).
: "Adipose-derived mesenchymal stem cells employed exosomes to attenuate AKI-CKD transition through tubular epithelial cell dependent Sox9 activation." dans: Oncotarget, Vol. 8, Issue 41, pp. 70707-70726, (2017) (PubMed).
: "MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3." dans: Oncotarget, Vol. 8, Issue 54, pp. 92801-92814, (2017) (PubMed).
: "Chikusetsu saponin IVa attenuates isoflurane-induced neurotoxicity and cognitive deficits via SIRT1/ERK1/2 in developmental rats." dans: American journal of translational research, Vol. 9, Issue 9, pp. 4288-4299, (2017) (PubMed).
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(Arg)9-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling." dans: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 138, (2018) (PubMed).
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- Antigène
- BAX (BCL2-Associated X Protein (BAX))
- Autre désignation
- BAX (BAX Produits)
- Synonymes
- anticorps BAX-ALPHA, anticorps bax-A, anticorps xBax, anticorps xlbax, anticorps BAX, anticorps bax, anticorps fj16e01, anticorps wu:fc50b10, anticorps wu:fj16e01, anticorps BCL2L4, anticorps zgc:112983, anticorps BCL2 associated X, apoptosis regulator, anticorps BCL2-associated X protein L homeolog, anticorps BCL2-associated X protein, anticorps bcl2-associated X protein, a, anticorps bcl2-associated X protein, b, anticorps BAX, anticorps bax.L, anticorps bax, anticorps baxa, anticorps Bax, anticorps baxb
- Sujet
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.,BCL2L4,BAX,Cancer,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Warburg Effect,Neuroscience,Neurodegenerative Diseases,BAX
- Poids moléculaire
- 4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa
- ID gène
- 581
- UniProt
- Q07812
- Pathways
- Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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