GLI1 anticorps

N° du produit ABIN6141127

Détail du produit anti-GLI1 anticorps

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human GLI1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-GLI1 (ABIN6141127)

Jin, Zhu, Cheng, Zhang: "Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway." dans: Journal of cellular biochemistry, Vol. 119, Issue 8, pp. 6882-6893, (2018) (PubMed).

Gao, Li, Li: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." dans: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).

Chang, Yang, Zheng, Li, Nie: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." dans: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).

Détails sur GLI1

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: GLI1 (GLI1 Produits)

Synonymes: anticorps GLI, anticorps Gli, anticorps Gli-1, anticorps gli1.1, anticorps AV235269, anticorps Zfp-5, anticorps Zfp5, anticorps GLI family zinc finger 1, anticorps GLI family zinc finger 1 S homeolog, anticorps GLI-Kruppel family member GLI1, anticorps GLI1, anticorps Gli1, anticorps gli1.S, anticorps gli1

Sujet: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.,GLI1,GLI,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI1

Poids moléculaire: 104 kDa/113 kDa/117 kDa

ID gène: 2735

UniProt: P08151

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis