IFT57 anticorps (AA 170-429)

N° du produit ABIN6142218

Détail du produit anti-IFT57 anticorps

Antigène: IFT57 (Intraflagellar Transport 57 Homolog (IFT57))

Épitope: AA 170-429

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFT57 est non-conjugé

Application: Western Blotting (WB)

Séquence: VEELEEESVA EDDAELTLNK VDEEFVEEET DNEENFIDLN VLKAQTYHLD MNETAKQEDI LESTTDAAEW SLEVERVLPQ LKVTIRTDNK DWRIHVDQMH QHRSGIESAL KETKGFLDKL HNEITRTLEK ISSREKYINN QLENLVQEYR AAQAQLSEAK ERYQQGNGGV TERTRLLSEV MEELEKVKQE MEEKGSSMTD GAPLVKIKQS LTKLKQETVE MDIRIGIVEH TLLQSKLKEK SNMTRNMHAT VIPEPATGFY

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 170-429 of human IFT57 (NP_060480.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IFT57

Antigène: IFT57 (Intraflagellar Transport 57 Homolog (IFT57))

Autre désignation: IFT57 (IFT57 Produits)

Synonymes: anticorps Esrrbl1, anticorps 4833420A15Rik, anticorps Hippi, anticorps MHS4R2, anticorps ESRRBL1, anticorps HIPPI, anticorps intraflagellar transport 57, anticorps intraflagellar transport 57 S homeolog, anticorps Ift57, anticorps IFT57, anticorps ift57.S

Sujet: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8 and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.,IFT57,ESRRBL1,HIPPI,MHS4R2,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,IFT57

Poids moléculaire: 49 kDa

ID gène: 55081

UniProt: Q9NWB7

Pathways: Signalisation Hedgehog, Positive Regulation of Endopeptidase Activity