PKC alpha anticorps (AA 523-672)

N° du produit ABIN6146197

L’anticorps Lapin Polyclonal anti-PKC alpha a été validé pour WB. Il convient pour détecter PKC alpha dans des échantillons de Humain.

Aperçu rapide pour PKC alpha anticorps (AA 523-672) (ABIN6146197)

Antigène: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PKC alpha anticorps

Épitope: AA 523-672

Séquence: AYGVLLYEML AGQPPFDGED EDELFQSIME HNVSYPKSLS KEAVSICKGL MTKHPAKRLG CGPEGERDVR EHAFFRRIDW EKLENREIQP PFKPKVCGKG AENFDKFFTR GQPVLTPPDQ LVIANIDQSD FEGFSYVNPQ FVHPILQSAV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 523-672 of human PKC alpha (NP_002728.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PKC alpha

Antigène: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Autre désignation: PRKCA

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.,PRKCA,AAG6,PKC-alpha,PKCA,PRKACA,PKC alpha,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,Phospholipase Signaling Pathway,Protein Kinase C Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Adhesion,Cytoskeleton,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,Cardiovascular,Heart,Hypertrophy,PRKCA

Poids moléculaire: 76 kDa

ID gène: 5578

UniProt: P17252

Pathways: Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling