WNT4 anticorps (AA 122-351)

N° du produit ABIN6150246

Détail du produit anti-WNT4 anticorps

Antigène: WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

Épitope: AA 122-351

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT4 est non-conjugé

Application: Western Blotting (WB)

Séquence: FAVTRACSSG ELEKCGCDRT VHGVSPQGFQ WSGCSDNIAY GVAFSQSFVD VRERSKGASS SRALMNLHNN EAGRKAILTH MRVECKCHGV SGSCEVKTCW RAVPPFRQVG HALKEKFDGA TEVEPRRVGS SRALVPRNAQ FKPHTDEDLV YLEPSPDFCE QDMRSGVLGT RGRTCNKTSK AIDGCELLCC GRGFHTAQVE LAERCSCKFH WCCFVKCRQC QRLVELHTCR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 122-351 of human WNT4 (NP_110388.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-WNT4 (ABIN6150246)

Zhang, Mehmood, Jiang, Yao, Iqbal, Waqas, Rehman, Li, Shen, Li: "Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens." dans: Environmental science and pollution research international, Vol. 25, Issue 28, pp. 28264-28274, (2019) (PubMed).

Détails sur WNT4

Antigène: WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

Autre désignation: WNT4 (WNT4 Produits)

Synonymes: anticorps CG4698, anticorps DWnt-4, anticorps DWnt4, anticorps Dm DWnt4, anticorps Dmel\\CG4698, anticorps Dwnt4, anticorps Wnt, anticorps Wnt-4, anticorps anon-EST:Liang-2.4, anticorps clone 2.4, anticorps wnt-4, anticorps wnt4, anticorps SERKAL, anticorps WNT-4, anticorps Xwnt4, anticorps xwnt-4, anticorps zgc:136737, anticorps Wnt family member 4, anticorps Wnt oncogene analog 4, anticorps wingless-type MMTV integration site family, member 4, anticorps wingless-type MMTV integration site family member 4 S homeolog, anticorps wingless-type MMTV integration site family, member 4a, anticorps WNT4, anticorps Wnt4, anticorps wnt4.S, anticorps wnt4a

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98 % amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.,WNT4,SERKAL,WNT-4,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,WNT4

Poids moléculaire: 32 kDa/39 kDa

ID gène: 54361

UniProt: P56705

Pathways: Signalisation WNT, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cell-Cell Junction Organization, Tube Formation