CFTR anticorps (AA 258-385) (CF®647)
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- Antigène Voir toutes CFTR Anticorps
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
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Épitope
- AA 258-385
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CFTR est conjugé à/à la CF®647
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Application
- Immunofluorescence (IF), ELISA, Coating (Coat)
- Fonction
- Mouse Monoclonal anti-CFTR CFTR/1644), CF647 Conjugate
- Attributs du produit
- This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human CFTR fragment (aa258-385) (exact sequence is proprietary)
- Clone
- CFTR-1644
- Isotype
- IgG1
- Top Product
- Discover our top product CFTR Anticorps primaire
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- Indications d'application
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Immunofluorescence 0.5-1 μg/mL
- ELISA For coating, order Ab without BSA
- Optimal dilution for a specific application should be determined by user
- Commentaires
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MOLT-4 cells. Pancreas, Kidney or Placenta.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
- Autre désignation
- CFTR (CFTR Produits)
- Synonymes
- anticorps ABC35, anticorps ABCC7, anticorps CF, anticorps CFTR/MRP, anticorps MRP7, anticorps TNR-CFTR, anticorps dJ760C5.1, anticorps CFTR, anticorps AW495489, anticorps Abcc7, anticorps RGD1561193, anticorps abc35, anticorps abcc7, anticorps cftr/mrp, anticorps mrp7, anticorps tnr-cftr, anticorps xcftr, anticorps si:dkey-270i2.2, anticorps cystic fibrosis transmembrane conductance regulator, anticorps cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7), anticorps CFTR, anticorps cftr-A, anticorps Cftr, anticorps cftr
- Poids moléculaire
- 165-170 kDa
- ID gène
- 1080
- UniProt
- P13569
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