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ITGA7 anticorps (N-Term)

ITGA7 Reactivité: Humain WB, FACS, IF, IHC (p) Hôte: Lapin Polyclonal RB52834 unconjugated
N° du produit ABIN6578121
  • Antigène Voir toutes ITGA7 Anticorps
    ITGA7 (Integrin, alpha 7 (ITGA7))
    Épitope
    • 14
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 247-279, N-Term
    Reactivité
    • 47
    • 19
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 8
    • 1
    Lapin
    Clonalité
    • 44
    • 8
    Polyclonal
    Conjugué
    • 29
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGA7 est non-conjugé
    Application
    • 35
    • 20
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ITGA7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 247-279 amino acids from the N-terminal region of human ITGA7.
    Clone
    RB52834
    Isotype
    Ig Fraction
  • Indications d'application
    IF: 1:25. WB: 1:2000. WB: 1:4000. IHC-P: 1:25. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    ITGA7 (Integrin, alpha 7 (ITGA7))
    Autre désignation
    ITGA7 (ITGA7 Produits)
    Synonymes
    anticorps [a]7, anticorps alpha7, anticorps integrin alpha 7, anticorps integrin subunit alpha 7, anticorps Itga7, anticorps ITGA7
    Sujet
    Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
    Poids moléculaire
    128948
    UniProt
    Q13683
    Pathways
    Integrin Complex
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