Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) anticorps

N° du produit ABIN6252268

Détail du produit

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Épitope: AA 356-475

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogène: Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.

Clone: SPTBN2-1584

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

IF: 0.5-1 μg/mL

IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

WB: 0.5-1 μg/mL



The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Spectrin beta III antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détail du antigène

Antigène: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Autre désignation: SPTBN2 (SPTBN2 Produits)

Synonymes: anticorps Spnb3, anticorps mKIAA0302, anticorps GTRAP41, anticorps SCA5, anticorps spectrin beta, non-erythrocytic 2, anticorps spectrin, beta, non-erythrocytic 2, anticorps Sptbn2, anticorps SPTBN2

Sujet: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alphaII (fodrin alpha) and spectrin betaI (fodrin beta) are present in other somatic cells. SPTBN2/Spectrin betaIII is highly homologous to both spectrin betaI and spectrin betaII. SPTBN2 is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.

ID gène: 6712

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis