beta-2 Microglobulin anticorps

N° du produit ABIN6252361

Détail du produit anti-beta-2 Microglobulin anticorps

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta-2 Microglobulin est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogène: Full length recombinant human protein was used as the immunogen for the B2M antibody.

Clone: SPM617

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Prediluted format: incubate for 30 min at RT (2)

Optimal dilution of the B2M antibody should be determined by the researcher.

1. Staining of formalin/paraffin tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur beta-2 Microglobulin

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Autre désignation: B2M (B2M Produits)

Synonymes: anticorps Ly-m11, anticorps beta2-m, anticorps beta2m, anticorps bwm, anticorps wu:fa94c05, anticorps wu:fb10a09, anticorps b2m-W01, anticorps b2m-W03, anticorps b2m-Z01, anticorps b2m-Z02, anticorps b2m-Z03, anticorps B2M, anticorps b2m, anticorps B2MG, anticorps wu:fb66f11, anticorps wu:fj01f08, anticorps zgc:64161, anticorps b-2-m, anticorps beta-2-microglobulin, anticorps beta-2 microglobulin, anticorps beta-2-microglobulin S homeolog, anticorps beta-2-microglobulin, like, anticorps B2M, anticorps B2m, anticorps b2m, anticorps b2m.S, anticorps b2ml

Sujet: Serum Beta-2 Microglobulin (B2M) levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma.

ID gène: 567

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process