CDK1 anticorps

N° du produit ABIN6252447

Détail du produit anti-CDK1 anticorps

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK1 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Does not react with Mouse or Rat

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for the CDK1 antibody.

Clone: CDVC2-1

Isotype: IgG2a kappa

Information d'application

Indications d'application: Immunofluorescence: 1-2 μg/mL

Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)

Titering of the CDK1 antibody may be required for optimal performance.

1. FFPE testing requires sections to be boiled in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur CDK1

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Autre désignation: CDK1 (CDK1 Produits)

Synonymes: anticorps CDC2, anticorps CDC28A, anticorps P34CDC2, anticorps Cdc2, anticorps Cdc2a, anticorps p34, anticorps cdc2, anticorps wu:fc30e01, anticorps zgc:92032, anticorps PSTAIR, anticorps cdc-2, anticorps cdc2-a, anticorps cdc28a, anticorps cdc2x1.1, anticorps p34cdc2, anticorps xcdc2, anticorps 5363, anticorps CDCDm, anticorps CDK1, anticorps CDK1/CDC2, anticorps CG5363, anticorps Cdk-1, anticorps Cdk1, anticorps Dcdc2, anticorps Dm cdc2, anticorps DmCdc2, anticorps DmCdk1, anticorps Dmcdc2, anticorps Dmel\\CG5363, anticorps cdc, anticorps cdc2Dm, anticorps cdk1, anticorps dCdk1, anticorps group 4, anticorps l(2)31Eh, anticorps CDC2A, anticorps CDC2AAT, anticorps CDK2, anticorps CDKA1, anticorps CDKA;1, anticorps CYCLIN-DEPENDENT KINASE A;1, anticorps cell division control 2, anticorps cdc2-b, anticorps cdc2a, anticorps cdc2x1.2, anticorps POL3, anticorps pold, anticorps cyclin dependent kinase 1, anticorps cyclin dependent kinase like 1, anticorps Cell division control protein 2 1, anticorps cyclin-dependent kinase 1, anticorps cyclin-dependent kinase 1 S homeolog, anticorps Cyclin-dependent kinase 1, anticorps cell division control 2, anticorps cell division control protein2 homolog, anticorps cyclin-dependent kinase 1 L homeolog, anticorps polymerase (DNA directed), delta 1, catalytic subunit L homeolog, anticorps cyclin-dependent protein kinase Cdk1/Cdc2, anticorps CDK1, anticorps CDKL1, anticorps POPTR_0004s14080g, anticorps Cdk1, anticorps cdk1, anticorps cdk1.S, anticorps CDC2, anticorps cdc2, anticorps cdk-1, anticorps cdk1.L, anticorps pold1.L

Sujet: Cyclin-Dependent Kinase 1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. [RefSeq]

ID gène: 983

UniProt: P06493

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA