TCF3 anticorps (Internal Region)

N° du produit ABIN6259214

Détail du produit anti-TCF3 anticorps

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: TCF3 Antibody detects endogenous levels of total TCF3.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TCF3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TCF3

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Autre désignation: TCF3 (TCF3 Produits)

Synonymes: anticorps E2A, anticorps E47, anticorps ITF1, anticorps TCF-3, anticorps VDIR, anticorps bHLHb21, anticorps tcf3a, anticorps zgc:113045, anticorps A1, anticorps AA408400, anticorps ALF2, anticorps AW209082, anticorps E12, anticorps E12/E47, anticorps ME2, anticorps Pan1, anticorps Pan2, anticorps Tcfe2a, anticorps bhlhb21, anticorps e2a, anticorps itf1, anticorps tcfe2a, anticorps vdir, anticorps xtcf-3, anticorps xtcf3, anticorps G12, anticorps TCF7L1, anticorps XE3, anticorps transcription factor 3, anticorps transcription factor 3b, anticorps transcription factor 3 L homeolog, anticorps transcription factor E2a, anticorps TCF3, anticorps tcf3b, anticorps Tcf3, anticorps tcf3.L, anticorps tcfe2a

Sujet:

Description: Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.

Gene: TCF3

Poids moléculaire: 68 kDa

ID gène: 6929

UniProt: P15923

Pathways: Signalisation WNT, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response