ABCG5 anticorps (Internal Region)
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- Antigène Voir toutes ABCG5 Anticorps
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ABCG5 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- ABCG5 Antibody detects endogenous levels of total ABCG5.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ABCG5, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ABCG5 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
- Autre désignation
- ABCG5 (ABCG5 Produits)
- Synonymes
- anticorps DDBDRAFT_0205617, anticorps DDBDRAFT_0215344, anticorps DDB_0205617, anticorps DDB_0215344, anticorps STSL, anticorps AW112016, anticorps cmp, anticorps sterolin-1, anticorps trac, anticorps ATP binding cassette subfamily G member 5, anticorps ATP-binding cassette, sub-family G (WHITE), member 5, anticorps ABC transporter G family protein, anticorps ABCG5, anticorps abcg5, anticorps abcG5, anticorps Abcg5
- Sujet
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Description: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane (PubMed:27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11138003, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11138003, PubMed:15054092). The heterodimer with ABCG8 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Gene: ABCG5
- Poids moléculaire
- 72 kDa
- ID gène
- 64240
- UniProt
- Q9H222
- Pathways
- Lipid Metabolism
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