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PUMA anticorps (Internal Region)

BBC3 Reactivité: Humain, Rat, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6260207
  • Antigène Voir toutes PUMA (BBC3) Anticorps
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Épitope
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 95
    • 40
    • 39
    • 16
    Humain, Rat, Souris
    Hôte
    • 92
    • 6
    • 1
    Lapin
    Clonalité
    • 82
    • 17
    Polyclonal
    Conjugué
    • 51
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PUMA est non-conjugé
    Application
    • 80
    • 34
    • 31
    • 21
    • 16
    • 14
    • 14
    • 13
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificité
    BBC3 Antibody detects endogenous levels of total BBC3.
    Homologie
    Pig,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human BBC3(PUMA), corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product BBC3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Zhang, Li, Wang, Li, Shi, Kan, Pang: "Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells." dans: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).

  • Antigène
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Autre désignation
    BBC3 (BBC3 Produits)
    Synonymes
    anticorps BBC3, anticorps Puma, anticorps JFY-1, anticorps JFY1, anticorps PUMA, anticorps PUMA/JFY1, anticorps BCL2 binding component 3, anticorps Bcl-2 binding component 3, anticorps BBC3, anticorps Bbc3, anticorps bbc3
    Sujet

    Description: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.

    Gene: BBC3

    Poids moléculaire
    20 kDa
    ID gène
    27113
    UniProt
    Q9BXH1
    Pathways
    Signalisation p53, Positive Regulation of Endopeptidase Activity
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