PUMA anticorps (Internal Region)
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- Antigène Voir toutes PUMA (BBC3) Anticorps
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Épitope
- Internal Region
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PUMA est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- BBC3 Antibody detects endogenous levels of total BBC3.
- Homologie
- Pig,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human BBC3(PUMA), corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product BBC3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells." dans: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).
: "
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Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells." dans: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).
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- Antigène
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Autre désignation
- BBC3 (BBC3 Produits)
- Synonymes
- anticorps BBC3, anticorps Puma, anticorps JFY-1, anticorps JFY1, anticorps PUMA, anticorps PUMA/JFY1, anticorps BCL2 binding component 3, anticorps Bcl-2 binding component 3, anticorps BBC3, anticorps Bbc3, anticorps bbc3
- Sujet
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Description: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Gene: BBC3
- Poids moléculaire
- 20 kDa
- ID gène
- 27113
- UniProt
- Q9BXH1
- Pathways
- Signalisation p53, Positive Regulation of Endopeptidase Activity
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