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IRF9 anticorps (Internal Region)

IRF9 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262658
  • Antigène Voir toutes IRF9 Anticorps
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Épitope
    • 15
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 49
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 43
    • 7
    • 1
    Lapin
    Clonalité
    • 45
    • 5
    Polyclonal
    Conjugué
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IRF9 est non-conjugé
    Application
    • 37
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificité
    IRF9 Antibody detects endogenous levels of total IRF9.
    Homologie
    Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human IRF9, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IRF9 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Autre désignation
    IRF9 (IRF9 Produits)
    Synonymes
    anticorps IRF-9, anticorps ISGF3, anticorps ISGF3G, anticorps p48, anticorps zgc:92097, anticorps Irf-9, anticorps Isgf3g, anticorps interferon regulatory factor 9, anticorps IRF9, anticorps irf9, anticorps Irf9
    Sujet

    Description: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    Gene: IRF9

    Poids moléculaire
    48 kDa
    ID gène
    10379
    UniProt
    Q00978
    Pathways
    Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C
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