IRF9 anticorps (Internal Region)
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- Antigène Voir toutes IRF9 Anticorps
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF9 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- IRF9 Antibody detects endogenous levels of total IRF9.
- Homologie
- Horse,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human IRF9, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product IRF9 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Autre désignation
- IRF9 (IRF9 Produits)
- Synonymes
- anticorps IRF-9, anticorps ISGF3, anticorps ISGF3G, anticorps p48, anticorps zgc:92097, anticorps Irf-9, anticorps Isgf3g, anticorps interferon regulatory factor 9, anticorps IRF9, anticorps irf9, anticorps Irf9
- Sujet
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Description: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Gene: IRF9
- Poids moléculaire
- 48 kDa
- ID gène
- 10379
- UniProt
- Q00978
- Pathways
- Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C
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