CCL2 anticorps (Internal Region)

N° du produit ABIN6263169

Détail du produit anti-CCL2 anticorps

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: MCP1 Antibody detects endogenous levels of total MCP1.

Homologie: Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-CCL2 (ABIN6263169)

Xia, Deng, Zhou, Shao, Yang, Sha, Zou: "Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction." dans: Transplant immunology, Vol. 48, pp. 18-25, (2018) (PubMed).

Qin, Qiao, Wang, Li, Li, Gong, Zhang, Fu: "An Extracellular Matrix-Mimicking Hydrogel for Full Thickness Wound Healing in Diabetic Mice." dans: Macromolecular bioscience, Vol. 18, Issue 7, pp. e1800047, (2018) (PubMed).

Pavlyashik, Zharikov, Kiselev: "[Comparative estimation of antilithogenic activity of porcine kidney derived biomedical substance and sodium citrate in experimental urolithiasis]." dans: Urologiia (Moscow, Russia : 1999), Issue 2, pp. 24-27, (2017) (PubMed).

Wang, Sun, Li, Deng, Zeng, Tao, Wang, Guan, Zhao: "Urinary MCP-1、HMGB1 increased in calcium nephrolithiasis patients and the influence of hypercalciuria on the production of the two cytokines." dans: Urolithiasis, Vol. 45, Issue 2, pp. 159-175, (2016) (PubMed).

Détails sur CCL2

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Autre désignation: CCL2 (CCL2 Produits)

Synonymes: anticorps GDCF-2, anticorps HC11, anticorps HSMCR30, anticorps MCAF, anticorps MCP-1, anticorps MCP1, anticorps SCYA2, anticorps SMC-CF, anticorps AI323594, anticorps JE, anticorps Scya2, anticorps Sigje, anticorps MCP-1A, anticorps MCP1A, anticorps C-C motif chemokine ligand 2, anticorps chemokine (C-C motif) ligand 2, anticorps C-C motif chemokine 2, anticorps CCL2, anticorps Ccl2, anticorps LOC101120093

Sujet:

Description: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Gene: CCL2

Poids moléculaire: 14 kDa

ID gène: 6347

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2