NCKAP1 anticorps (Internal Region)

N° du produit ABIN6263539

Détail du produit anti-NCKAP1 anticorps

Antigène: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCKAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: NCKAP1 Antibody detects endogenous levels of total NCKAP1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NCKAP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NCKAP1

Antigène: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Autre désignation: NCKAP1 (NCKAP1 Produits)

Synonymes: anticorps HEM2, anticorps NAP1, anticorps NAP125, anticorps p125Nap1, anticorps C79304, anticorps H19, anticorps Hem-2, anticorps Hem2, anticorps Nap1, anticorps mKIAA0587, anticorps mh19, anticorps NCK associated protein 1, anticorps NCK-associated protein 1, anticorps NCK-associated protein 1 L homeolog, anticorps NCKAP1, anticorps Nckap1, anticorps nckap1.L

Sujet:

Description: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Gene: NCKAP1

Poids moléculaire: 115-125 kDa

ID gène: 10787

UniProt: Q9Y2A7

Pathways: Signalisation RTK, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis