NFATC2IP anticorps (Internal Region)
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- Antigène Voir toutes NFATC2IP Anticorps
- NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))
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Épitope
- Internal Region
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFATC2IP est non-conjugé
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- NFATc2IP Antibody detects endogenous levels of total NFATc2IP.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human NFATc2IP, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NFATC2IP Anticorps primaire
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- Indications d'application
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))
- Autre désignation
- NFATC2IP (NFATC2IP Produits)
- Synonymes
- anticorps wu:fj84d09, anticorps NFATC2IP, anticorps D7Ertd304e, anticorps NIP45, anticorps ESC2, anticorps RAD60, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein, anticorps nuclear factor of activated T-cells 2 interacting protein, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein, anticorps nfatc2ip, anticorps NFATC2IP, anticorps Nfatc2ip
- Sujet
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Description: In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter, this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity).
Gene: NFATC2IP
- Poids moléculaire
- 48kDa
- ID gène
- 84901
- UniProt
- Q8NCF5
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