Presenilin 2 anticorps (Internal Region)

N° du produit ABIN6264464

Détail du produit anti-Presenilin 2 anticorps

Antigène: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Presenilin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Presenilin 2 Antibody detects endogenous levels of total Presenilin 2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Presenilin 2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Presenilin 2

Antigène: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Autre désignation: PSEN2 (PSEN2 Produits)

Synonymes: anticorps AD3L, anticorps AD4, anticorps CMD1V, anticorps PS2, anticorps STM2, anticorps ALG-3, anticorps Ad4h, anticorps Alg3, anticorps PS-2, anticorps Psnl2, anticorps pre2, anticorps zf-PS2, anticorps PSNL2, anticorps PSEN2, anticorps ad4, anticorps ps2, anticorps ad3l, anticorps stm2, anticorps Ps2, anticorps presenilin 2, anticorps presenilin 2 S homeolog, anticorps presenilin 2 (Alzheimer disease 4), anticorps trefoil factor 1, anticorps PSEN2, anticorps Psen2, anticorps psen2, anticorps psen2.S, anticorps Tff1

Sujet:

Description: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

Gene: PSEN2

Poids moléculaire: 50kDa

ID gène: 5664

UniProt: P49810

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway