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14-3-3 sigma/SFN anticorps (Internal Region)

SFN Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265025
  • Antigène Voir toutes 14-3-3 sigma/SFN (SFN) Anticorps
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Épitope
    • 15
    • 13
    • 11
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 103
    • 35
    • 28
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 93
    • 9
    • 2
    • 1
    Lapin
    Clonalité
    • 88
    • 17
    Polyclonal
    Conjugué
    • 48
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp 14-3-3 sigma/SFN est non-conjugé
    Application
    • 86
    • 44
    • 38
    • 23
    • 17
    • 15
    • 14
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificité
    14-3-3 sigma Antibody detects endogenous levels of total 14-3-3 sigma.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human 14-3-3 sigma, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SFN Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Autre désignation
    SFN (SFN Produits)
    Synonymes
    anticorps YWHAS, anticorps Er, anticorps Mme1, anticorps Ywhas, anticorps stratifin, anticorps SFN, anticorps Sfn
    Sujet

    Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

    Gene: SFN

    Poids moléculaire
    28kDa
    ID gène
    2810
    UniProt
    P31947
    Pathways
    Signalisation p53, Myometrial Relaxation and Contraction
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