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TICAM1 anticorps (Internal Region)

TICAM1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265566
  • Antigène Voir toutes TICAM1 Anticorps
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Épitope
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 25
    • 9
    • 2
    • 2
    Humain, Souris, Rat
    Hôte
    • 22
    • 4
    • 3
    Lapin
    Clonalité
    • 25
    • 4
    Polyclonal
    Conjugué
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TICAM1 est non-conjugé
    Application
    • 20
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    TICAM1 Antibody detects endogenous levels of total TICAM1.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human TICAM1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TICAM1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Autre désignation
    TICAM1 (TICAM1 Produits)
    Synonymes
    anticorps IIAE6, anticorps MyD88-3, anticorps PRVTIRB, anticorps TICAM-1, anticorps TRIF, anticorps AW046014, anticorps AW547018, anticorps trif, anticorps toll like receptor adaptor molecule 1, anticorps toll-like receptor adaptor molecule 1, anticorps TICAM1, anticorps Ticam1, anticorps ticam1
    Sujet

    Description: Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

    Gene: TICAM1

    Poids moléculaire
    76kDa
    ID gène
    148022
    UniProt
    Q8IUC6
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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