TRF1 anticorps (Internal Region)
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- Antigène Voir toutes TRF1 (TERF1) Anticorps
- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TRF1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- TRF1 Antibody detects endogenous levels of total TRF1.
- Homologie
- Horse,Sheep
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human TRF1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TERF1 Anticorps primaire
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- Indications d'application
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
- Autre désignation
- TERF1 (TERF1 Produits)
- Synonymes
- anticorps PIN2, anticorps TRBF1, anticorps TRF, anticorps TRF1, anticorps hTRF1-AS, anticorps t-TRF1, anticorps wu:fb74c04, anticorps TERF1, anticorps DKFZp459A0713, anticorps Pin2, anticorps Trbf1, anticorps Trf1, anticorps terf1, anticorps trf1, anticorps telomeric repeat binding factor 1, anticorps telomeric repeat binding factor (NIMA-interacting) 1, anticorps telomeric repeat binding factor (NIMA-interacting) 1 L homeolog, anticorps TERF1, anticorps Terf1, anticorps terf1, anticorps Trf1, anticorps terf1.L
- Sujet
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Description: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
Gene: TERF1
- Poids moléculaire
- 50kDa
- ID gène
- 7013
- UniProt
- P54274
- Pathways
- Cycle Cellulaire, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
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