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Histone 3 anticorps (H3K27me3)

H3 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ChIP, IP, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6266167
  • Antigène Voir toutes Histone 3 (H3) Anticorps
    Histone 3 (H3)
    Épitope
    • 60
    • 47
    • 44
    • 44
    • 40
    • 36
    • 35
    • 35
    • 34
    • 34
    • 34
    • 32
    • 29
    • 29
    • 28
    • 27
    • 26
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    • 23
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    • 12
    • 11
    • 11
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    H3K27me3
    Reactivité
    • 1376
    • 939
    • 860
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 26
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 1183
    • 246
    • 12
    • 4
    Lapin
    Clonalité
    • 1108
    • 336
    • 1
    Polyclonal
    Conjugué
    • 797
    • 81
    • 65
    • 64
    • 63
    • 63
    • 63
    • 62
    • 34
    • 33
    • 22
    • 17
    • 17
    • 17
    • 17
    • 17
    • 12
    • 1
    Cet anticorp Histone 3 est non-conjugé
    Application
    • 1034
    • 401
    • 372
    • 310
    • 239
    • 188
    • 174
    • 171
    • 163
    • 151
    • 136
    • 127
    • 117
    • 48
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Specificité
    Tri-Methyl-Histone H3 (Lys27)/H3K27me3 Antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys27.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthetic methylated peptide derived from human Tri-Methyl-Histone H3 around the methylation site of Lys27.
    Isotype
    IgG
    Top Product
    Discover our top product H3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, IP 1:50-1:200, CHIP 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Chen, Liu, Lu, Luo, Wang, Wang, Cai, Yang, Xie, Zhang, Yun: "HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis." dans: Molecular oncology, Vol. 11, Issue 9, pp. 1225-1240, (2018) (PubMed).

  • Antigène
    Histone 3 (H3)
    Autre désignation
    HIST3H3 (H3 Produits)
    Synonymes
    anticorps H-3, anticorps histocompatibility 3, anticorps H3
    Sujet

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST3H3

    Poids moléculaire
    15kDa
    ID gène
    8290
    UniProt
    Q16695
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